Novel inhibitor of influenza non-structural protein 1 blocks multi-cycle replication in an RNase L-dependent manner

Influenza virus non-structural protein 1 (NS1) is the centrepiece of the viral response to the host interferon (IFN) system. NS1 has been demonstrated previously to be a potential therapeutic target for antiviral therapy by identification of specific small-molecule inhibitors. This study demonstrate...

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Detalles Bibliográficos
Autores principales: Walkiewicz, Marcin P., Basu, Dipanwita, Jablonski, Joseph J., Geysen, H. Mario, Engel, Daniel A.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052532/
https://www.ncbi.nlm.nih.gov/pubmed/20881091
http://dx.doi.org/10.1099/vir.0.025015-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052532/
https://www.ncbi.nlm.nih.gov/pubmed/20881091
http://dx.doi.org/10.1099/vir.0.025015-0

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