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Amino acid changes within the Bunyamwera virus nucleocapsid protein differentially affect the mRNA transcription and RNA replication activities of assembled ribonucleoprotein templates

The genome of Bunyamwera virus (BUNV) comprises three RNA segments that are encapsidated by the virus-encoded nucleocapsid (N) protein to form ribonucleoprotein (RNP) complexes. These RNPs are the functional templates for RNA synthesis by the virus-encoded RNA-dependent RNA polymerase (RdRp). We inv...

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Detalles Bibliográficos
Autores principales: Walter, Cheryl T., Costa Bento, Diana F., Guerrero Alonso, Ana, Barr, John N.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052533/
https://www.ncbi.nlm.nih.gov/pubmed/20943890
http://dx.doi.org/10.1099/vir.0.024240-0