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The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism
Bunyamwera virus NSs protein is involved in the inhibition of cellular transcription and the interferon (IFN) response, and it interacts with the Med8 component of Mediator. A spontaneous mutant of a recombinant NSs-deleted Bunyamwera virus (rBUNdelNSs2) was identified and characterized. This mutant...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Society for General Microbiology
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052537/ https://www.ncbi.nlm.nih.gov/pubmed/20427562 http://dx.doi.org/10.1099/vir.0.021774-0 |