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The N-terminus of Bunyamwera orthobunyavirus NSs protein is essential for interferon antagonism

Bunyamwera virus NSs protein is involved in the inhibition of cellular transcription and the interferon (IFN) response, and it interacts with the Med8 component of Mediator. A spontaneous mutant of a recombinant NSs-deleted Bunyamwera virus (rBUNdelNSs2) was identified and characterized. This mutant...

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Detalles Bibliográficos
Autores principales:	van Knippenberg, Ingeborg, Carlton-Smith, Charlie, Elliott, Richard M.
Formato:	Texto
Lenguaje:	English
Publicado:	Society for General Microbiology 2010
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052537/ https://www.ncbi.nlm.nih.gov/pubmed/20427562 http://dx.doi.org/10.1099/vir.0.021774-0

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