Cargando…

Transcription factor Spi-B binds unique sequences present in the tandem repeat promoter/enhancer of JC virus and supports viral activity

Progressive multifocal leukoencephalopathy (PML) is an often fatal demyelinating disease caused by lytic infection of oligodendrocytes with JC virus (JCV). The development of PML in non-immunosuppressed individuals is a growing concern with reports of mortality in patients treated with mAb therapies...

Descripción completa

Detalles Bibliográficos
Autores principales: Marshall, Leslie J., Dunham, Lisa, Major, Eugene O.
Formato: Texto
Lenguaje:English
Publicado: Society for General Microbiology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052566/
https://www.ncbi.nlm.nih.gov/pubmed/20826618
http://dx.doi.org/10.1099/vir.0.023184-0