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Efficient production of soluble recombinant single chain Fv fragments by a Pseudomonas putida strain KT2440 cell factory

BACKGROUND: Recombinant antibody fragments have a wide range of applications in research, diagnostics and therapy. For many of these, small fragments like single chain fragment variables (scFv) function well and can be produced inexpensively in bacterial expression systems. Although Escherichia coli...

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Detalles Bibliográficos
Autores principales: Dammeyer, Thorben, Steinwand, Miriam, Krüger, Sarah-C, Dübel, Stefan, Hust, Michael, Timmis, Kenneth N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053225/
https://www.ncbi.nlm.nih.gov/pubmed/21338491
http://dx.doi.org/10.1186/1475-2859-10-11