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Myelination in the absence of UDP-galactose:ceramide galactosyl-transferase and fatty acid 2 -hydroxylase

BACKGROUND: The sphingolipids galactosylceramide (GalCer) and sulfatide are major myelin components and are thought to play important roles in myelin function. The importance of GalCer and sulfatide has been validated using UDP-galactose:ceramide galactosyltransferase-deficient (Cgt(-/-)) mice, whic...

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Detalles Bibliográficos
Autores principales: Meixner, Marion, Jungnickel, Julia, Grothe, Claudia, Gieselmann, Volkmar, Eckhardt, Matthias
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053264/
https://www.ncbi.nlm.nih.gov/pubmed/21366909
http://dx.doi.org/10.1186/1471-2202-12-22