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Crawling Cells Can Close Wounds without Purse Strings or Signaling

When a gash or gouge is made in a confluent layer of epithelial cells, the cells move to fill in the “wound.” In some cases, such as in wounded embryonic chick wing buds, the movement of the cells is driven by cortical actin contraction (i.e., a purse string mechanism). In adult tissue, though, cell...

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Detalles Bibliográficos
Autores principales: Lee, Pilhwa, Wolgemuth, Charles W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053312/
https://www.ncbi.nlm.nih.gov/pubmed/21423710
http://dx.doi.org/10.1371/journal.pcbi.1002007