Noise Contributions in an Inducible Genetic Switch: A Whole-Cell Simulation Study

Stochastic expression of genes produces heterogeneity in clonal populations of bacteria under identical conditions. We analyze and compare the behavior of the inducible lac genetic switch using well-stirred and spatially resolved simulations for Escherichia coli cells modeled under fast and slow-gro...

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Detalles Bibliográficos
Autores principales: Roberts, Elijah, Magis, Andrew, Ortiz, Julio O., Baumeister, Wolfgang, Luthey-Schulten, Zaida
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053318/
https://www.ncbi.nlm.nih.gov/pubmed/21423716
http://dx.doi.org/10.1371/journal.pcbi.1002010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053318/
https://www.ncbi.nlm.nih.gov/pubmed/21423716
http://dx.doi.org/10.1371/journal.pcbi.1002010

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