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Noise Contributions in an Inducible Genetic Switch: A Whole-Cell Simulation Study
Stochastic expression of genes produces heterogeneity in clonal populations of bacteria under identical conditions. We analyze and compare the behavior of the inducible lac genetic switch using well-stirred and spatially resolved simulations for Escherichia coli cells modeled under fast and slow-gro...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053318/ https://www.ncbi.nlm.nih.gov/pubmed/21423716 http://dx.doi.org/10.1371/journal.pcbi.1002010 |