Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

Nonalcoholic fatty liver disease (NAFLD) clusters in families, but the only known common genetic variants influencing risk are near PNPLA3. We sought to identify additional genetic variants influencing NAFLD using genome-wide association (GWA) analysis of computed tomography (CT) measured hepatic st...

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Detalles Bibliográficos
Autores principales: Speliotes, Elizabeth K., Yerges-Armstrong, Laura M., Wu, Jun, Hernaez, Ruben, Kim, Lauren J., Palmer, Cameron D., Gudnason, Vilmundur, Eiriksdottir, Gudny, Garcia, Melissa E., Launer, Lenore J., Nalls, Michael A., Clark, Jeanne M., Mitchell, Braxton D., Shuldiner, Alan R., Butler, Johannah L., Tomas, Marta, Hoffmann, Udo, Hwang, Shih-Jen, Massaro, Joseph M., O'Donnell, Christopher J., Sahani, Dushyant V., Salomaa, Veikko, Schadt, Eric E., Schwartz, Stephen M., Siscovick, David S., Voight, Benjamin F., Carr, J. Jeffrey, Feitosa, Mary F., Harris, Tamara B., Fox, Caroline S., Smith, Albert V., Kao, W. H. Linda, Hirschhorn, Joel N., Borecki, Ingrid B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053321/
https://www.ncbi.nlm.nih.gov/pubmed/21423719
http://dx.doi.org/10.1371/journal.pgen.1001324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053321/
https://www.ncbi.nlm.nih.gov/pubmed/21423719
http://dx.doi.org/10.1371/journal.pgen.1001324

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