Cargando…

KIR Polymorphisms Modulate Peptide-Dependent Binding to an MHC Class I Ligand with a Bw6 Motif

Molecular interactions between killer immunoglobulin-like receptors (KIRs) and their MHC class I ligands play a central role in the regulation of natural killer (NK) cell responses to viral pathogens and tumors. Here we identify Mamu-A1*00201 (Mamu-A*02), a common MHC class I molecule in the rhesus...

Descripción completa

Detalles Bibliográficos
Autores principales: Colantonio, Arnaud D., Bimber, Benjamin N., Neidermyer, William J., Reeves, R. Keith, Alter, Galit, Altfeld, Marcus, Johnson, R. Paul, Carrington, Mary, O'Connor, David H., Evans, David T.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053351/
https://www.ncbi.nlm.nih.gov/pubmed/21423672
http://dx.doi.org/10.1371/journal.ppat.1001316