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Therapy with Sodium Stibogluconate in Stearylamine-Bearing Liposomes Confers Cure against SSG-Resistant Leishmania donovani in BALB/c Mice

BACKGROUND: Resistance of Leishmania donovani to pentavalent antimonials, the first-line treatment of visceral leishmaniasis (VL), has become a critical issue worldwide. Second-line and new drugs are also not devoid of limitations. Suitable drug-delivery systems can improve the mode of administratio...

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Detalles Bibliográficos
Autores principales: Roychoudhury, Jayeeta, Sinha, Roma, Ali, Nahid
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053369/
https://www.ncbi.nlm.nih.gov/pubmed/21423750
http://dx.doi.org/10.1371/journal.pone.0017376