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Critical Role of the Rb Family in Myoblast Survival and Fusion

The tumor suppressor Rb is thought to control cell proliferation, survival and differentiation. We recently showed that differentiating Rb-deficient mouse myoblasts can fuse to form short myotubes that quickly collapse through a mechanism involving autophagy, and that autophagy inhibitors or hypoxia...

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Detalles Bibliográficos
Autores principales: Ciavarra, Giovanni, Ho, Andrew T., Cobrinik, David, Zacksenhaus, Eldad
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053373/
https://www.ncbi.nlm.nih.gov/pubmed/21423694
http://dx.doi.org/10.1371/journal.pone.0017682