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Short Telomeres Compromise β-Cell Signaling and Survival

The genetic factors that underlie the increasing incidence of diabetes with age are poorly understood. We examined whether telomere length, which is inherited and known to shorten with age, plays a role in the age-dependent increased incidence of diabetes. We show that in mice with short telomeres,...

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Detalles Bibliográficos
Autores principales: Guo, Nini, Parry, Erin M., Li, Luo-Sheng, Kembou, Frant, Lauder, Naudia, Hussain, Mehboob A., Berggren, Per-Olof, Armanios, Mary
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053388/
https://www.ncbi.nlm.nih.gov/pubmed/21423765
http://dx.doi.org/10.1371/journal.pone.0017858