Facile labelling of an anti-epidermal growth factor receptor Nanobody with (68)Ga via a novel bifunctional desferal chelate for immuno-PET

PURPOSE: The ∼15 kDa variable domains of camelid heavy-chain-only antibodies (called Nanobodies®) have the flexibility to be formatted as monovalent, monospecific, multivalent or multispecific single chain proteins with either fast or slow pharmacokinetics. We report the evaluation of the fast kinet...

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Detalles Bibliográficos
Autores principales: Vosjan, Maria J. W. D., Perk, Lars R., Roovers, Rob C., Visser, Gerard W. M., Stigter-van Walsum, Marijke, van Bergen en Henegouwen, Paul M. P., van Dongen, Guus A. M. S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053459/
https://www.ncbi.nlm.nih.gov/pubmed/21210114
http://dx.doi.org/10.1007/s00259-010-1700-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053459/
https://www.ncbi.nlm.nih.gov/pubmed/21210114
http://dx.doi.org/10.1007/s00259-010-1700-1

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