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Exon Array Analysis using re-defined probe sets results in reliable identification of alternatively spliced genes in non-small cell lung cancer

BACKGROUND: Treatment of non-small cell lung cancer with novel targeted therapies is a major unmet clinical need. Alternative splicing is a mechanism which generates diverse protein products and is of functional relevance in cancer. RESULTS: In this study, a genome-wide analysis of the alteration of...

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Detalles Bibliográficos
Autores principales: Langer, Wolfram, Sohler, Florian, Leder, Gabriele, Beckmann, Georg, Seidel, Henrik, Gröne, Jörn, Hummel, Michael, Sommer, Anette
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053589/
https://www.ncbi.nlm.nih.gov/pubmed/21118496
http://dx.doi.org/10.1186/1471-2164-11-676