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Light microscopic and electron microscopic features of cyclosporine nephrotoxicity in rats.

In order to clarify morphologic changes associated with cyclosporine (CS) nephrotoxicity, CS in ethyl alcohol at 25 mg/kg/day i.p. was administered to male Sprague-Dawley rats for periods of 1 to 8 weeks. Mean systolic BP was slightly increased in the CS group at 4 weeks (p < 0.05), but there was...

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Detalles Bibliográficos
Autores principales: Kim, J. Y., Suh, K. S.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054149/
https://www.ncbi.nlm.nih.gov/pubmed/8750061