5' CpG island methylation of p16 is associated with absence of p16 expression in glioblastomas.

Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is an important mechanism in the inactivation of p16INK4 tumor suppressor gene. This study is designed to clarify the significance of p16INK4 hypermethylation in 23 cases of glioblastomas (GBMs)...

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Detalles Bibliográficos
Autores principales: Park, S. H., Jung, K. C., Ro, J. Y., Kang, G. H., Khang, S. K.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2000
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054673/
https://www.ncbi.nlm.nih.gov/pubmed/11068994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054673/
https://www.ncbi.nlm.nih.gov/pubmed/11068994

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