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Overexpression of promyelocytic leukemia protein and alteration of PML nuclear bodies in early stage of hepatocarcinogenesis.

Promyelocytic leukemia protein (PML) is a major component of PML nuclear bodies (PML NBs). Fusion of promyelocytic leukemia alpha gene (PML) with retinoic acid receptor gene with the t (15;17) translocation causes disassembly of PML NBs, leading to development of acute promyelocytic leukemia. In con...

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Detalles Bibliográficos
Autores principales: Yoon, G. S., Yu, E.
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3054776/
https://www.ncbi.nlm.nih.gov/pubmed/11511788