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Effects of MK-801 (dizocilpine) on brain cell membrane function and energy metabolism in experimental Escherichia coli meningitis in the newborn piglet.

We evaluated the efficacy of non-competitive N-methyl-D-aspartate receptor antagonist MK-801 (dizocilpine) as an adjuvant therapy in experimental neonal bacterial meningitis. Meningitis was induced by injecting 10(6) colony forming units of Escherichia coli into the cisterna magna. MK-801 3 mg/kg wa...

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Detalles Bibliográficos
Autores principales: Ko, Sun Young, Shim, Jae Won, Kim, Sung Shin, Kim, Mi Jung, Chang, Yun Sil, Park, Won Soon, Shin, Son Moon, Lee, Mun Hyang
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055019/
https://www.ncbi.nlm.nih.gov/pubmed/12692422