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Characterization of mutator pathway in younger-age-onset colorectal adenocarcinomas.

The high-frequency microsatellite instability (MSI-H) phenotype, frequently identified in hereditary nonpolyposis colorectal cancer (HNPCC), also accounts for approximately 15% of sporadic colorectal cancers. Microsatellite instability (MSI) occurs from the mutational inactivation of the DNA mismatc...

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Detalles Bibliográficos
Autores principales: Roh, Seon Ae, Kim, Hee Cheol, Kim, Jung Seon, Kim, Jin Cheon
Formato: Texto
Lenguaje:English
Publicado: Korean Academy of Medical Sciences 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055043/
https://www.ncbi.nlm.nih.gov/pubmed/12808326