Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins

BACKGROUND: Pregnancy associated malaria is a severe clinical syndrome associated with sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental binding is mediated by VAR2CSA, which adheres to chondroitin sulphate A (CSA). VAR2CSA is a large and polymorphic protein tha...

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Detalles Bibliográficos
Autores principales: Avril, Marion, Cartwright, Megan M, Hathaway, Marianne J, Smith, Joseph D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055221/
https://www.ncbi.nlm.nih.gov/pubmed/21314945
http://dx.doi.org/10.1186/1475-2875-10-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055221/
https://www.ncbi.nlm.nih.gov/pubmed/21314945
http://dx.doi.org/10.1186/1475-2875-10-36

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