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Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins

BACKGROUND: Pregnancy associated malaria is a severe clinical syndrome associated with sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental binding is mediated by VAR2CSA, which adheres to chondroitin sulphate A (CSA). VAR2CSA is a large and polymorphic protein tha...

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Detalles Bibliográficos
Autores principales:	Avril, Marion, Cartwright, Megan M, Hathaway, Marianne J, Smith, Joseph D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055221/ https://www.ncbi.nlm.nih.gov/pubmed/21314945 http://dx.doi.org/10.1186/1475-2875-10-36

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