Cargando…

Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins

BACKGROUND: Pregnancy associated malaria is a severe clinical syndrome associated with sequestration of Plasmodium falciparum-infected erythrocytes in the placenta. Placental binding is mediated by VAR2CSA, which adheres to chondroitin sulphate A (CSA). VAR2CSA is a large and polymorphic protein tha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Avril, Marion, Cartwright, Megan M, Hathaway, Marianne J, Smith, Joseph D
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055221/ https://www.ncbi.nlm.nih.gov/pubmed/21314945 http://dx.doi.org/10.1186/1475-2875-10-36

Ejemplares similares

Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions
por: Gangnard, Stéphane, et al.
Publicado: (2015)

Antibodies to a Full-Length VAR2CSA Immunogen Are Broadly Strain-Transcendent but Do Not Cross-Inhibit Different Placental-Type Parasite Isolates
por: Avril, Marion, et al.
Publicado: (2011)

Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers
por: Fodjo, Barriere A. Y., et al.
Publicado: (2016)

Epitope Mapping and Topographic Analysis of VAR2CSA DBL3X Involved in P. falciparum Placental Sequestration
por: Dahlbäck, Madeleine, et al.
Publicado: (2006)

Insight into Antigenic Diversity of VAR2CSA-DBL5ε Domain from Multiple Plasmodium falciparum Placental Isolates
por: Gnidehou, Sédami, et al.
Publicado: (2010)

Identification and Characterization of B-Cell Epitopes in the DBL4ε Domain of VAR2CSA
por: Ditlev, Sisse B., et al.
Publicado: (2012)

Strain-Transcendent Immune Response to Recombinant Var2CSA DBL5-ε Domain Block P. falciparum Adhesion to Placenta-Derived BeWo Cells under Flow Conditions
por: Fernandez, Pablo, et al.
Publicado: (2010)

Sequence Polymorphism, Segmental Recombination and Toggling Amino Acid Residues within the DBL3X Domain of the VAR2CSA Placental Malaria Antigen
por: Talundzic, Eldin, et al.
Publicado: (2012)

Plasmodium falciparum Variability and Immune Evasion Proceed from Antigenicity of Consensus Sequences from DBL6ε; Generalization to All DBL from VAR2CSA
por: Deloron, Philippe, et al.
Publicado: (2013)

Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites
por: Fernandez, Pablo, et al.
Publicado: (2008)

Down-selection of the VAR2CSA DBL1-2 expressed in E. coli as a lead antigen for placental malaria vaccine development
por: Chêne, Arnaud, et al.
Publicado: (2018)

Polymorphic Molecular Signatures in Variable Regions of the Plasmodium falciparum var2csa DBL3x Domain Are Associated with Virulence in Placental Malaria
por: Talundzic, Eldin, et al.
Publicado: (2022)

Production, crystallization and X-ray diffraction analysis of two nanobodies against the Duffy binding-like (DBL) domain DBL6∊-FCR3 of the Plasmodium falciparum VAR2CSA protein. Corrigendum
por: Vuchelen, Anneleen, et al.
Publicado: (2013)

Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A
por: Singh, Kavita, et al.
Publicado: (2008)

Structural Comparison of Two CSPG-Binding DBL Domains from the VAR2CSA Protein Important in Malaria during Pregnancy
por: Khunrae, Pongsak, et al.
Publicado: (2009)

Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses
por: Gbédandé, Komi, et al.
Publicado: (2016)

Llama immunization with full-length VAR2CSA generates cross-reactive and inhibitory single-domain antibodies against the DBL1X domain
por: Nunes-Silva, Sofia, et al.
Publicado: (2014)

A Sequence in Subdomain 2 of DBL1α of Plasmodium falciparum Erythrocyte Membrane Protein 1 Induces Strain Transcending Antibodies
por: Blomqvist, Karin, et al.
Publicado: (2013)

Analysis of var Gene Transcription Pattern Using DBLα Tags
por: Andisi, Kivisi C., et al.
Publicado: (2022)

A paradoxical population structure of var DBLα types in Africa
por: Tan, Mun Hua, et al.
Publicado: (2023)

Antibodies to full-length and the DBL5 domain of VAR2CSA in pregnant women after long-term implementation of intermittent preventive treatment in Etoudi, Cameroon
por: Djontu, Jean Claude, et al.
Publicado: (2020)

Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris
por: Avril, Marion, et al.
Publicado: (2009)

Unravelling var complexity: Relationship between DBLα types and var genes in Plasmodium falciparum
por: Tan, Mun Hua, et al.
Publicado: (2022)

Towards the Rational Design of a Candidate Vaccine against Pregnancy Associated Malaria: Conserved Sequences of the DBL6ε Domain of VAR2CSA
por: Badaut, Cyril, et al.
Publicado: (2010)

Antibody Levels to Plasmodium falciparum Erythrocyte Membrane Protein 1-DBLγ11 and DBLδ-1 Predict Reduction in Parasite Density
por: Araj, Brittany N., et al.
Publicado: (2021)

Induction of Epithelial Mesenchimal Transition and Vasculogenesis in the Lenses of Dbl Oncogene Transgenic Mice
por: Fardin, Paolo, et al.
Publicado: (2009)

High Avidity Antibodies to Full-Length VAR2CSA Correlate with Absence of Placental Malaria
por: Tutterrow, Yeung Lo, et al.
Publicado: (2012)

METU-DBL: a cost effective proton irradiation facility
por: Karadöller, E, et al.
Publicado: (2023)

Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag
por: Stucke, Emily M., et al.
Publicado: (2019)

Phagocytosis-inducing antibodies to Plasmodium falciparum upon immunization with a recombinant PfEMP1 NTS-DBL1α domain
por: Quintana, Maria del Pilar, et al.
Publicado: (2016)

Pretest setup installation of the METU-DBL project to perform space radiation tests
por: Demirkoz, M Bilge, et al.
Publicado: (2017)

Doublet identification in single-cell sequencing data using scDblFinder
por: Germain, Pierre-Luc, et al.
Publicado: (2022)

Recombinant DBL2β-PfEMP1 of the Indonesian Plasmodium falciparum induces immune responses in Wistar rats
por: Rachmania, Sheilla, et al.
Publicado: (2021)

Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA
por: Dorin-Semblat, Dominique, et al.
Publicado: (2019)

Analysis of antibody induction upon immunization with distinct NTS-DBL1α-domains of PfEMP1 from rosetting Plasmodium falciparum parasites
por: Angeletti, Davide, et al.
Publicado: (2013)

Antibody response to a new member of the DBL family (EBP2) after a brief Plasmodium vivax exposure
por: Lima, Bárbara A. S., et al.
Publicado: (2022)

A Novel DBL-Domain of the P. falciparum 332 Molecule Possibly Involved in Erythrocyte Adhesion
por: Moll, Kirsten, et al.
Publicado: (2007)

Caenorhabditis elegans DBL-1/BMP Regulates Lipid Accumulation via Interaction with Insulin Signaling
por: Clark, James F., et al.
Publicado: (2017)

The Evolutionary Landscape of Dbl-Like RhoGEF Families: Adapting Eukaryotic Cells to Environmental Signals
por: Fort, Philippe, et al.
Publicado: (2017)

B-Cell Epitopes in NTS-DBL1α of PfEMP1 Recognized by Human Antibodies in Rosetting Plasmodium falciparum
por: Albrecht, Letusa, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_t7dpq6cftovf9o5tn731poee7m