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Squamocin modulates histone H3 phosphorylation levels and induces G(1 )phase arrest and apoptosis in cancer cells

BACKGROUND: Histone modifications in tumorigenesis are increasingly recognized as important epigenetic factors leading to cancer. Increased phosphorylation levels of histone H3 as a result of aurora B and pMSK1 overexpression were observed in various tumors. We selected aurora B and MSK1 as represen...

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Detalles Bibliográficos
Autores principales: Lee, Chien-Chih, Lin, Yi-Hsiung, Chang, Wen-Hsin, Lin, Pei-Chin, Wu, Yang-Chang, Chang, Jan-Gowth
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055232/
https://www.ncbi.nlm.nih.gov/pubmed/21299907
http://dx.doi.org/10.1186/1471-2407-11-58