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Squamocin modulates histone H3 phosphorylation levels and induces G(1 )phase arrest and apoptosis in cancer cells
BACKGROUND: Histone modifications in tumorigenesis are increasingly recognized as important epigenetic factors leading to cancer. Increased phosphorylation levels of histone H3 as a result of aurora B and pMSK1 overexpression were observed in various tumors. We selected aurora B and MSK1 as represen...
Autores principales: | Lee, Chien-Chih, Lin, Yi-Hsiung, Chang, Wen-Hsin, Lin, Pei-Chin, Wu, Yang-Chang, Chang, Jan-Gowth |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055232/ https://www.ncbi.nlm.nih.gov/pubmed/21299907 http://dx.doi.org/10.1186/1471-2407-11-58 |
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