Structural basis of high fidelity DNA synthesis by yeast DNA polymerase delta

DNA polymerase δ (Polδ) is a high fidelity polymerase that plays a central role in replication from yeast to humans. We present here the crystal structure of the catalytic subunit of yeast Polδ in ternary complex with a template-primer and an incoming nucleotide. The structure, determined at 2.0Å re...

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Detalles Bibliográficos
Autores principales: Swan, Michael K., Johnson, Robert E., Prakash, Louise, Prakash, Satya, Aggarwal, Aneel K.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055789/
https://www.ncbi.nlm.nih.gov/pubmed/19718023
http://dx.doi.org/10.1038/nsmb.1663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055789/
https://www.ncbi.nlm.nih.gov/pubmed/19718023
http://dx.doi.org/10.1038/nsmb.1663

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