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Experimental design, preprocessing, normalization and differential expression analysis of small RNA sequencing experiments
Prior to the advent of new, deep sequencing methods, small RNA (sRNA) discovery was dependent on Sanger sequencing, which was time-consuming and limited knowledge to only the most abundant sRNA. The innovation of large-scale, next-generation sequencing has exponentially increased knowledge of the bi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055805/ https://www.ncbi.nlm.nih.gov/pubmed/21356093 http://dx.doi.org/10.1186/1758-907X-2-2 |