Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site

Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous antimicrotubule agents are prepared every year, and the determination of their binding affinity to tubulin requires the use of purified tubulins and radiolabeled ligands. Such...

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Detalles Bibliográficos
Autores principales: Fortin, Sébastien, Lacroix, Jacques, Côté, Marie-France, Moreau, Emmanuel, Petitclerc, Éric, C-Gaudreault, René
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055821/
https://www.ncbi.nlm.nih.gov/pubmed/21406120
http://dx.doi.org/10.1007/s12575-010-9029-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055821/
https://www.ncbi.nlm.nih.gov/pubmed/21406120
http://dx.doi.org/10.1007/s12575-010-9029-5

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