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High-throughput 454 resequencing for allele discovery and recombination mapping in Plasmodium falciparum
BACKGROUND: Knowledge of the origins, distribution, and inheritance of variation in the malaria parasite (Plasmodium falciparum) genome is crucial for understanding its evolution; however the 81% (A+T) genome poses challenges to high-throughput sequencing technologies. We explore the viability of th...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055840/ https://www.ncbi.nlm.nih.gov/pubmed/21324207 http://dx.doi.org/10.1186/1471-2164-12-116 |