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In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1

BACKGROUND: The transcription factor Nkx2-1 (also known as TTF-1, Titf1 or T/EBP) contains two apparently redundant activation domains and is post-translationally modified by phosphorylation. We have generated mouse mutant strains to assess the roles of the two activation domains and of phosphorylat...

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Detalles Bibliográficos
Autores principales: Silberschmidt, Daniel, Rodriguez-Mallon, Alina, Mithboakar, Prathiba, Calì, Gaetano, Amendola, Elena, Sanges, Remo, Zannini, Mariastella, Scarfò, Marzia, De Luca, Pasquale, Nitsch, Lucio, Di Lauro, Roberto, De Felice, Mario
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055846/
https://www.ncbi.nlm.nih.gov/pubmed/21345181
http://dx.doi.org/10.1186/1471-213X-11-9