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PrtT-Regulated Proteins Secreted by Aspergillus fumigatus Activate MAPK Signaling in Exposed A549 Lung Cells Leading to Necrotic Cell Death

Aspergillus fumigatus is the most commonly encountered mold pathogen of humans, predominantly infecting the respiratory system. Colonization and penetration of the lung alveolar epithelium is a key but poorly understood step in the infection process. This study focused on identifying the transcripti...

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Detalles Bibliográficos
Autores principales: Sharon, Haim, Amar, David, Levdansky, Emma, Mircus, Gabriel, Shadkchan, Yana, Shamir, Ron, Osherov, Nir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055868/
https://www.ncbi.nlm.nih.gov/pubmed/21412410
http://dx.doi.org/10.1371/journal.pone.0017509