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Vaccination with Brucella abortus Recombinant In Vivo-Induced Antigens Reduces Bacterial Load and Promotes Clearance in a Mouse Model for Infection

Current vaccines used for the prevention of brucellosis are ineffective in inducing protective immunity in animals that are chronically infected with Brucella abortus, such as elk. Using a gene discovery approach, in vivo-induced antigen technology (IVIAT) on B. abortus, we previously identified ten...

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Detalles Bibliográficos
Autores principales: Lowry, Jake E., Isaak, Dale D., Leonhardt, Jack A., Vernati, Giulia, Pate, Jessie C., Andrews, Gerard P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055878/
https://www.ncbi.nlm.nih.gov/pubmed/21412420
http://dx.doi.org/10.1371/journal.pone.0017425