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Vaccination with Brucella abortus Recombinant In Vivo-Induced Antigens Reduces Bacterial Load and Promotes Clearance in a Mouse Model for Infection
Current vaccines used for the prevention of brucellosis are ineffective in inducing protective immunity in animals that are chronically infected with Brucella abortus, such as elk. Using a gene discovery approach, in vivo-induced antigen technology (IVIAT) on B. abortus, we previously identified ten...
Autores principales: | Lowry, Jake E., Isaak, Dale D., Leonhardt, Jack A., Vernati, Giulia, Pate, Jessie C., Andrews, Gerard P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055878/ https://www.ncbi.nlm.nih.gov/pubmed/21412420 http://dx.doi.org/10.1371/journal.pone.0017425 |
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