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Gene-Trap Mutagenesis Identifies Mammalian Genes Contributing to Intoxication by Clostridium perfringens ε-Toxin

The Clostridium perfringens ε-toxin is an extremely potent toxin associated with lethal toxemias in domesticated ruminants and may be toxic to humans. Intoxication results in fluid accumulation in various tissues, most notably in the brain and kidneys. Previous studies suggest that the toxin is a po...

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Detalles Bibliográficos
Autores principales: Ivie, Susan E., Fennessey, Christine M., Sheng, Jinsong, Rubin, Donald H., McClain, Mark S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055893/
https://www.ncbi.nlm.nih.gov/pubmed/21412435
http://dx.doi.org/10.1371/journal.pone.0017787