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Gene-Trap Mutagenesis Identifies Mammalian Genes Contributing to Intoxication by Clostridium perfringens ε-Toxin
The Clostridium perfringens ε-toxin is an extremely potent toxin associated with lethal toxemias in domesticated ruminants and may be toxic to humans. Intoxication results in fluid accumulation in various tissues, most notably in the brain and kidneys. Previous studies suggest that the toxin is a po...
Autores principales: | Ivie, Susan E., Fennessey, Christine M., Sheng, Jinsong, Rubin, Donald H., McClain, Mark S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055893/ https://www.ncbi.nlm.nih.gov/pubmed/21412435 http://dx.doi.org/10.1371/journal.pone.0017787 |
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