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A Chemical Method for Labeling Lysine Methyltransferase Substrates

Several protein lysine methyltransferases (PKMTs) modify histones to regulate chromatin-dependent cellular processes, such as transcription, DNA replication and DNA damage repair. PKMTs are likely to have many additional substrates in addition to histones, but relatively few nonhistone substrates ha...

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Detalles Bibliográficos
Autores principales: Binda, Olivier, Boyce, Michael, Rush, Jason S, Palaniappan, Krishnan K, Bertozzi, Carolyn R, Gozani, Or
Formato: Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056122/
https://www.ncbi.nlm.nih.gov/pubmed/21243721
http://dx.doi.org/10.1002/cbic.201000433