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The STING pathway and regulation of innate immune signaling in response to DNA pathogens
The innate immune system has evolved a variety of sensing mechanisms to detect and counter microbial invasion. These include the Toll-like receptor (TLR), cytoplasmic, nucleotide binding oligomerization domain (NOD)-like receptor and RIG-I-like helicase (RLH) pathways. However, how the cell detects...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SP Birkhäuser Verlag Basel
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056141/ https://www.ncbi.nlm.nih.gov/pubmed/21161320 http://dx.doi.org/10.1007/s00018-010-0605-2 |