Dose-Levels and First Signs of Efficacy in Contemporary Oncology Phase 1 Clinical Trials

PURPOSE: Phase 1 trials play a crucial role in oncology by translating laboratory science into efficient therapies. Molecular targeted agents (MTA) differ from traditional cytotoxics in terms of both efficacy and toxicity profiles. Recent reports suggest that higher doses are not essential to produc...

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Detalles Bibliográficos
Autores principales: Ferte, Charles, Soria, Jean-Charles, Penel, Nicolas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056556/
https://www.ncbi.nlm.nih.gov/pubmed/21415927
http://dx.doi.org/10.1371/journal.pone.0016633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056556/
https://www.ncbi.nlm.nih.gov/pubmed/21415927
http://dx.doi.org/10.1371/journal.pone.0016633

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