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Predicting Pancreas Cell Fate Decisions and Reprogramming with a Hierarchical Multi-Attractor Model
Cell fate reprogramming, such as the generation of insulin-producing β cells from other pancreas cells, can be achieved by external modulation of key transcription factors. However, the known gene regulatory interactions that form a complex network with multiple feedback loops make it increasingly d...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056652/ https://www.ncbi.nlm.nih.gov/pubmed/21423725 http://dx.doi.org/10.1371/journal.pone.0014752 |