TGFβ1 enhances MAD1 expression and stimulates promoter-bound Pol II phosphorylation: basic functions of C/EBP, SP and SMAD3 transcription factors

BACKGROUND: The MAD1 protein, a member of the MYC/MAX/MAD network of transcriptional regulators, controls cell proliferation, differentiation and apoptosis. MAD1 functions as a transcriptional repressor, one direct target gene being the tumor suppressor PTEN. Repression of this gene is critical to m...

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Detalles Bibliográficos
Autores principales: Hein, Nadine, Jiang, Kan, Cornelissen, Christian, Lüscher, Bernhard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056803/
https://www.ncbi.nlm.nih.gov/pubmed/21345218
http://dx.doi.org/10.1186/1471-2199-12-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056803/
https://www.ncbi.nlm.nih.gov/pubmed/21345218
http://dx.doi.org/10.1186/1471-2199-12-9

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