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Citrus flavonoids repress the mRNA for stearoyl-CoA desaturase, a key enzyme in lipid synthesis and obesity control, in rat primary hepatocytes

Citrus flavonoids have been shown to decrease plasma lipid levels, improve glucose tolerance, and attenuate obesity. One possible mechanism underlying these physiological effects is reduction of hepatic levels of the mRNA for stearoyl-CoA desaturase-1 (SCD1), since repression of this enzyme reduces...

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Detalles Bibliográficos
Autores principales: Nichols, LaNita A, Jackson, Daniel E, Manthey, John A, Shukla, Shivendra D, Holland, Lené J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056818/
https://www.ncbi.nlm.nih.gov/pubmed/21345233
http://dx.doi.org/10.1186/1476-511X-10-36