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Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage

BACKGROUND: The adhesion of Plasmodium falciparum parasitized red blood cell (PRBC) to human endothelial cells (EC) induces inflammatory processes, coagulation cascades, oxidative stress and apoptosis. These pathological processes are suspected to be responsible for the blood-brain-barrier and other...

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Detalles Bibliográficos
Autores principales: Taoufiq, Zacharie, Pino, Paco, N'dilimabaka, Nadine, Arrouss, Issam, Assi, Serge, Soubrier, Florent, Rebollo, Angelita, Mazier, Dominique
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056843/
https://www.ncbi.nlm.nih.gov/pubmed/21356073
http://dx.doi.org/10.1186/1475-2875-10-52