Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study

BACKGROUND: Multicentre randomized controlled trials (RCTs) routinely use randomization and analysis stratified by centre to control for differences between centres and to improve precision. No consensus has been reached on how to best analyze correlated continuous outcomes in such settings. Our obj...

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Detalles Bibliográficos
Autores principales: Chu, Rong, Thabane, Lehana, Ma, Jinhui, Holbrook, Anne, Pullenayegum, Eleanor, Devereaux, Philip James
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056845/
https://www.ncbi.nlm.nih.gov/pubmed/21338524
http://dx.doi.org/10.1186/1471-2288-11-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056845/
https://www.ncbi.nlm.nih.gov/pubmed/21338524
http://dx.doi.org/10.1186/1471-2288-11-21

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