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Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study
BACKGROUND: Multicentre randomized controlled trials (RCTs) routinely use randomization and analysis stratified by centre to control for differences between centres and to improve precision. No consensus has been reached on how to best analyze correlated continuous outcomes in such settings. Our obj...
Autores principales: | Chu, Rong, Thabane, Lehana, Ma, Jinhui, Holbrook, Anne, Pullenayegum, Eleanor, Devereaux, Philip James |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056845/ https://www.ncbi.nlm.nih.gov/pubmed/21338524 http://dx.doi.org/10.1186/1471-2288-11-21 |
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