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Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes

A wide range of microorganisms can replicate in macrophages, and cell entry of these pathogens via non-neutralising IgG antibody complexes can result in increased intracellular infection through idiosyncratic Fcγ-receptor signalling. The activation of Fcγ receptors usually leads to phagocytosis. Par...

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Detalles Bibliográficos
Autores principales: Halstead, Scott B, Mahalingam, Suresh, Marovich, Mary A, Ubol, Sukathida, Mosser, David M
Formato: Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057165/
https://www.ncbi.nlm.nih.gov/pubmed/20883967
http://dx.doi.org/10.1016/S1473-3099(10)70166-3