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Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
A wide range of microorganisms can replicate in macrophages, and cell entry of these pathogens via non-neutralising IgG antibody complexes can result in increased intracellular infection through idiosyncratic Fcγ-receptor signalling. The activation of Fcγ receptors usually leads to phagocytosis. Par...
Autores principales: | Halstead, Scott B, Mahalingam, Suresh, Marovich, Mary A, Ubol, Sukathida, Mosser, David M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057165/ https://www.ncbi.nlm.nih.gov/pubmed/20883967 http://dx.doi.org/10.1016/S1473-3099(10)70166-3 |
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