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Stereo-selective inhibition of transient receptor potential TRPC5 cation channels by neuroactive steroids
BACKGROUND AND PURPOSE: Transient receptor potential canonical 5 (TRPC5) channels are widely expressed, including in the CNS, where they potentiate fear responses. They also contribute to other non-selective cation channels that are stimulated by G-protein-coupled receptor agonists and lipid and red...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Science Inc
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057289/ https://www.ncbi.nlm.nih.gov/pubmed/21108630 http://dx.doi.org/10.1111/j.1476-5381.2010.01136.x |