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Programming the magnitude and persistence of antibody responses with innate immunity

Many successful vaccines induce persistent antibody responses that can last a lifetime. The mechanisms by which they do so remain unclear, but emerging evidence suggests that they activate dendritic cells (DCs) via Toll-like receptors (TLRs)1,2. For example, the yellow fever vaccine YF-17D, one of t...

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Detalles Bibliográficos
Autores principales: Kasturi, Sudhir Pai, Skountzou, Ioanna, Albrecht, Randy A., Koutsonanos, Dimitrios, Hua, Tang, Nakaya, Helder, Ravindran, Rajesh, Stewart, Shelley, Alam, Munir, Kwissa, Marcin, Villinger, Francois, Murthy, Niren, Steel, John, Jacob, Joshy, Hogan, Robert J., García-Sastre, Adolfo, Compans, Richard, Pulendran, Bali
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057367/
https://www.ncbi.nlm.nih.gov/pubmed/21350488
http://dx.doi.org/10.1038/nature09737