Structural Changes of Envelope Proteins During Alphavirus Fusion

Alphaviruses are enveloped RNA viruses that have a diameter of about 700 Å and can be lethal human pathogens1 (Fig. 1). Entry of virus into host cells by endocytosis is controlled by two envelope glycoproteins, E1 and E2. The E2-E1 heterodimers form 80 trimeric spikes on the icosahedral virus surfac...

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Detalles Bibliográficos
Autores principales: Li, Long, Jose, Joyce, Xiang, Ye, Kuhn, Richard J., Rossmann, Michael G.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057476/
https://www.ncbi.nlm.nih.gov/pubmed/21124457
http://dx.doi.org/10.1038/nature09546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057476/
https://www.ncbi.nlm.nih.gov/pubmed/21124457
http://dx.doi.org/10.1038/nature09546

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